Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689534 | 0.83 | PTPRZ1 (0.58) | PTPRZ1POLBMAPTTDP1NPC1 | |
| SCHEMBL30386687 | 0.81 | PTPRZ1 (0.66) | PTPRZ1TDP1PTPN1MAOAMAOB | |
| SCHEMBL14102978 | 0.80 | NPC1 (0.61) | POLBTDP1NPC1RAB9AHPGD | |
| SCHEMBL6685855 | 0.79 | PTPRZ1 (0.77) | PTPRZ1MAPTTDP1NPC1RAB9A | |
| SCHEMBL190184 | 0.78 | HPGD (0.58) | POLBMAPTTDP1NPC1RAB9A | |
| SCHEMBL1508320 | 0.77 | CYP2D6 (0.53) | PTPN1MAOAMAOBMRGPRX4 | |
| SCHEMBL14339304 | 0.74 | TDP1 (0.46) | POLBMAPTTDP1 | |
| SCHEMBL1564072 | 0.73 | HPGD (0.46) | MAPTRAB9AHPGDMAOAMAOB | |
| SCHEMBL23004615 | 0.73 | MAOB (0.63) | POLBMAPTMAOAMAOB | |
| SCHEMBL6233787 | 0.72 | PTPRZ1 (0.57) | PTPRZ1MAPTTDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |