Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233787 | 0.85 | PTPRZ1 (0.57) | PTPRZ1ALDH1A1TUBB1NPC1RAB9A | |
| SCHEMBL5885604 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TUBB1NPC1RAB9ATDP1 | |
| SCHEMBL6231724 | 0.83 | PTPRZ1 (0.61) | PTPRZ1TUBB1NPC1RAB9ATDP1 | |
| SCHEMBL31591495 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TUBB1NPC1RAB9ATDP1 | |
| SCHEMBL30885463 | 0.81 | PTPRZ1 (0.62) | PTPRZ1ALDH1A1TDP1MAOBMRGPRX4 | |
| SCHEMBL14367331 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TUBB1NPC1RAB9ATDP1 | |
| SCHEMBL31533148 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TUBB1NPC1RAB9ATDP1 | |
| SCHEMBL435043 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TUBB1NPC1RAB9ATDP1 | |
| SCHEMBL21370452 | 0.78 | NPC1 (0.61) | ALDH1A1TUBB1NPC1RAB9ATDP1 | |
| SCHEMBL6688713 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TUBB1NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |