Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689534 | 0.85 | PTPRZ1 (0.58) | PTPRZ1TUBB1LMNAALDH1A1MAPT | |
| SCHEMBL6234931 | 0.83 | MAOB (0.49) | TUBB1ERN1NPC1RAB9ATDP1 | |
| SCHEMBL6233232 | 0.81 | MAOB (0.54) | TUBB1LMNAALDH1A1MAPTHPGD | |
| SCHEMBL6230803 | 0.79 | ALDH1A1 (0.57) | PTPRZ1LMNAALDH1A1MAPTHPGD | |
| SCHEMBL30885463 | 0.79 | PTPRZ1 (0.62) | PTPRZ1ALDH1A1TDP1PTPN1ABCB1 | |
| SCHEMBL1745424 | 0.78 | MAOB (0.53) | TUBB1MAPTSMN1; SMN2L3MBTL1ERN1 | |
| SCHEMBL6685855 | 0.76 | PTPRZ1 (0.77) | PTPRZ1LMNAALDH1A1MAPTHPGD | |
| SCHEMBL16096556 | 0.76 | ERN1 (0.43) | TUBB1MAPTSMN1; SMN2L3MBTL1ERN1 | |
| SCHEMBL6692112 | 0.75 | CD274 (0.53) | PTPRZ1PTPN1PDCD1CD274 | |
| SCHEMBL6686473 | 0.73 | MAOB (0.47) | PTPRZ1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |