SCHEMBL6231862

SCHEMBL6231862

C=CC(=O)NS(=O)(=O)c1cc(O)ccc1C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
GAA P10253 3/20 0.46
TSHR P16473 1/20 0.46
LMNA P02545 2/20 0.45
GFER P55789 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PKM P14618 1/20 0.40
MEP1B Q16820 1/20 0.39
HSD17B2 P37059 1/20 0.38
ALKBH2 Q6NS38 1/20 0.37
ALKBH3 Q96Q83 1/20 0.37
FTO Q9C0B1 1/20 0.37
CYTH2 Q99418 1/20 0.36
IDH1 O75874 2/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
TGM2 P21980 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9202081 0.81 ALDH1A1 (0.50) ALDH1A1GAATSHRLMNAGFER
SCHEMBL960240 0.80 CA1 (0.48) ALDH1A1GAALMNASMN1; SMN2ALKBH2
SCHEMBL6232117 0.79 ALDH1A1 (0.46) ALDH1A1GAATSHRLMNAGFER
SCHEMBL9176275 0.78 LMNA (0.57) ALDH1A1GAATSHRLMNAALKBH2
SCHEMBL9175750 0.78 LMNA (0.72) ALDH1A1GAATSHRLMNASMN1; SMN2
SCHEMBL9176599 0.78 LMNA (0.53) ALDH1A1GAATSHRLMNAGFER
SCHEMBL10913560 0.77 GAA (0.56) ALDH1A1GAATSHRLMNAGFER
SCHEMBL8752517 0.76 ALDH1A1 (0.52) ALDH1A1GAATSHRGFERSMN1; SMN2
SCHEMBL8752459 0.76 CA12 (0.47) ALDH1A1GAATSHRLMNASMN1; SMN2
SCHEMBL758273 0.76 TSHR (0.48) ALDH1A1GAATSHRLMNAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179427-B1 Planographic printing original plate FUJI PHOTO FILM CO LTD (JP) 2005-10-26 EP claimed
EP-1038668-B1 Photosensitive composition and planographic printing plate precursor using same FUJI PHOTO FILM CO LTD (JP) 2005-05-25 EP claimed
EP-0914964-B1 Positive type photosensitive composition for infrared lasers FUJI PHOTO FILM CO LTD (JP) 2004-12-29 EP claimed
EP-0909657-B1 A positive type photosensitive image-forming material for an infrared laser FUJI PHOTO FILM CO LTD (JP) 2003-06-18 EP claimed