Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYTH2 | Q99418 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685394 | 0.81 | BRD4 (0.51) | TSHRALDH1A1GAAMEP1BSMN1; SMN2 | |
| SCHEMBL7834037 | 0.78 | ALDH1A1 (0.48) | TSHRALDH1A1GAAMEP1BSMN1; SMN2 | |
| SCHEMBL9005826 | 0.78 | ALDH1A1 (0.54) | TSHRMAPK1ALDH1A1GAAKDM4E | |
| SCHEMBL4070788 | 0.78 | TSHR (0.49) | TSHRMAPK1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL10913560 | 0.77 | GAA (0.56) | TSHRMAPK1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8469458 | 0.76 | CA12 (0.50) | TSHRALDH1A1GAACYP1A2MEP1B | |
| SCHEMBL6231862 | 0.76 | ALDH1A1 (0.46) | TSHRALDH1A1GAAMEP1BSMN1; SMN2 | |
| SCHEMBL9853187 | 0.76 | KDM4E (0.50) | TSHRMAPK1ALDH1A1GAAKDM4E | |
| SCHEMBL743630 | 0.75 | LMNA (0.65) | TSHRMAPK1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL1032718 | 0.75 | KDM4E (0.60) | TSHRALDH1A1GAAKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151331-B1 | LOW-PERMEABILITY LAMINATE, AND PNEUMATIC TIRE UTILIZING THE SAME | YOKOHAMA RUBBER CO LTD (JP) | 2012-03-21 | — | — | EP | claimed |