Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.54 |
| ▸ | TRAP1 | Q12931 | 7/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230180 | 0.86 | TRAP1 (0.44) | DPP8DPP9DPP7TRAP1NAMPT | |
| SCHEMBL6232130 | 0.85 | TRAP1 (0.38) | DPP8DPP9DPP7TRAP1HSP90B1 | |
| SCHEMBL5068829 | 0.82 | NOTUM (0.52) | DPP8DPP9DPP7NAMPTDPP4 | |
| SCHEMBL6229746 | 0.82 | ABHD6 (0.55) | DPP8TRAP1HSP90B1NAMPTABHD6 | |
| SCHEMBL3478866 | 0.81 | DPP8 (0.60) | DPP8DPP9DPP7TRAP1HSP90B1 | |
| SCHEMBL3429846 | 0.79 | DPP8 (0.53) | DPP8DPP9DPP7TRAP1HSP90B1 | |
| SCHEMBL8207795 | 0.76 | DPP8 (0.57) | DPP8DPP9DPP7TRAP1HSP90B1 | |
| SCHEMBL8404042 | 0.76 | NOTUM (0.61) | DPP8DPP9DPP7TRAP1HSP90B1 | |
| SCHEMBL8221404 | 0.76 | DDB1 (0.55) | DPP8DPP9DPP7TRAP1HSP90B1 | |
| SCHEMBL6230796 | 0.75 | DPP9 (0.59) | DPP8DPP9DPP7KCNH2TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |