Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232130 | 0.87 | TRAP1 (0.38) | TRAP1DPP8DPP9DPP7NOTUM | |
| SCHEMBL6231874 | 0.86 | DPP8 (0.54) | TRAP1DPP8DPP9DPP7ABHD6 | |
| SCHEMBL5068829 | 0.85 | NOTUM (0.52) | DPP8DPP9DPP7NOTUMCYP3A4 | |
| SCHEMBL6229746 | 0.84 | ABHD6 (0.55) | TRAP1DPP8SLC6A9CYP2C9ABHD6 | |
| SCHEMBL18376168 | 0.80 | TRAP1 (0.49) | TRAP1DPP8DPP9DPP7NOTUM | |
| SCHEMBL13473657 | 0.77 | RIPK1 (0.53) | TRAP1NOTUMMEN1KMT2ASLC6A9 | |
| SCHEMBL27908431 | 0.77 | TRAP1 (0.51) | TRAP1DPP8DPP9DPP7NOTUM | |
| SCHEMBL6230084 | 0.76 | SMO (0.33) | DPP7KMT2AALDH1A1HPGDDPP4 | |
| SCHEMBL6229458 | 0.75 | DPP8 (0.51) | DPP8DPP9DPP7MEN1KMT2A | |
| SCHEMBL6253251 | 0.75 | NOTUM (0.58) | DPP8DPP7NOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |