Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 3/20 | 0.41 |
| ▸ | PDE6D | O43924 | 1/20 | 0.41 |
| ▸ | PDE6A | P16499 | 1/20 | 0.41 |
| ▸ | PDE6G | P18545 | 1/20 | 0.41 |
| ▸ | PDE6B | P35913 | 1/20 | 0.41 |
| ▸ | PDE6C | P51160 | 1/20 | 0.41 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824046 | 0.80 | DAO (0.62) | DAOALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL18575786 | 0.79 | DAO (0.58) | DAOALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL1378586 | 0.78 | RXFP1 (0.46) | ALDH1A1MAPTTP53 | |
| SCHEMBL4150766 | 0.76 | MEN1 (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL9974826 | 0.76 | TSHR (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL29941396 | 0.75 | CA12 (0.53) | ALDH1A1KMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL7128827 | 0.75 | CA12 (0.53) | ALDH1A1KMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL1238984 | 0.74 | DAO (1.00) | DAOALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7135259 | 0.73 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6231890 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052312-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | disclosed |