Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5435816 | 0.84 | KDM4E (0.63) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7462175 | 0.83 | ALDH1A1 (0.83) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7437043 | 0.82 | HTR3E (0.61) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11828707 | 0.81 | ALDH1A1 (0.70) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1790843 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11826856 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9535544 | 0.80 | KDM4E (1.00) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9262842 | 0.78 | ALDH1A1 (0.89) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9254043 | 0.78 | ALDH1A1 (0.89) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30197876 | 0.78 | ALDH1A1 (0.89) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059356-A2 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-24 | — | — | WO | claimed |