Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18601076 | 0.88 | KMT2A (0.50) | ARTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6235089 | 0.86 | ALDH1A1 (0.50) | ARTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL18600867 | 0.84 | AR (0.44) | ARTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2362378 | 0.82 | MAOA (0.58) | ARTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1647131 | 0.82 | AR (0.44) | ARTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4909005 | 0.82 | SMN1; SMN2 (0.57) | ARTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8836039 | 0.79 | POLB (0.59) | ARTP53POLBMAPT | |
| SCHEMBL23004615 | 0.78 | MAOB (0.63) | POLBMAPT | |
| SCHEMBL6702861 | 0.78 | ALDH1A1 (0.49) | KMT2AMEN1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL275398 | 0.77 | RAB9A (0.48) | KMT2AMEN1SMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |