Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22622336 | 0.89 | L3MBTL3 (0.70) | L3MBTL3L3MBTL1HPGDALDH1A1TSHR | |
| SCHEMBL14320950 | 0.86 | PKM (0.57) | L3MBTL1KDM4EHPGDALDH1A1TSHR | |
| SCHEMBL6899447 | 0.83 | HPGD (0.61) | L3MBTL3L3MBTL1HPGDALDH1A1TSHR | |
| SCHEMBL7218802 | 0.83 | HPGD (0.73) | L3MBTL3L3MBTL1HPGDALDH1A1TSHR | |
| SCHEMBL264516 | 0.82 | HPGD (0.76) | L3MBTL3L3MBTL1KDM4EHPGDALDH1A1 | |
| SCHEMBL10197843 | 0.81 | HPGD (0.71) | L3MBTL3L3MBTL1KDM4EHPGDALDH1A1 | |
| SCHEMBL4503263 | 0.81 | L3MBTL3 (0.60) | L3MBTL3L3MBTL1HPGDALDH1A1TSHR | |
| SCHEMBL29941490 | 0.81 | HPGD (0.71) | L3MBTL3L3MBTL1KDM4EHPGDALDH1A1 | |
| SCHEMBL1590985 | 0.80 | HPGD (0.80) | KDM4EHPGDALDH1A1TSHRCA12 | |
| SCHEMBL12156421 | 0.80 | HPGD (0.80) | KDM4EHPGDALDH1A1TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |