SCHEMBL6899447

SCHEMBL6899447

NC(=O)c1ccc2cc(C(=O)N3CCCCCC3)ccc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 10/20 0.61
ALDH1A1 P00352 1/20 0.61
L3MBTL3 Q96JM7 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
HRH3 Q9Y5N1 1/20 0.56
TSHR P16473 3/20 0.53
RECQL P46063 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
LCK P06239 1/20 0.51
CA12 O43570 2/20 0.51
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA7 P43166 2/20 0.51
CA9 Q16790 2/20 0.51
CA14 Q9ULX7 2/20 0.51
GRIA3 P42263 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22622336 0.89 L3MBTL3 (0.70) HPGDALDH1A1L3MBTL3L3MBTL1HRH3
Terephthalamide SCHEMBL198417 0.85 HPGD (0.62) HPGDALDH1A1L3MBTL3L3MBTL1TSHR
SCHEMBL6902996 0.85 HPGD (0.66) HPGDALDH1A1L3MBTL3L3MBTL1TSHR
SCHEMBL538527 0.85 HPGD (0.66) HPGDALDH1A1L3MBTL3L3MBTL1TSHR
SCHEMBL472245 0.85 HPGD (0.66) HPGDALDH1A1L3MBTL3L3MBTL1TSHR
SCHEMBL10197843 0.85 HPGD (0.71) HPGDALDH1A1L3MBTL3L3MBTL1TSHR
SCHEMBL369227 0.85 HPGD (0.66) HPGDALDH1A1L3MBTL3L3MBTL1TSHR
SCHEMBL538600 0.85 HPGD (0.66) HPGDALDH1A1L3MBTL3L3MBTL1TSHR
SCHEMBL472260 0.85 HPGD (0.66) HPGDALDH1A1L3MBTL3L3MBTL1TSHR
SCHEMBL367274 0.85 HPGD (0.66) HPGDALDH1A1L3MBTL3L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735082-B1 Polyphthalamide resin compositions SOLVAY ADVANCED POLYMERS LLC (US) 2004-05-26 EP disclosed
US-6306951-B1 TOUGHNESS, ELONGATION BP CORPORATION NORTH AMERICA INC. 2001-10-23 US disclosed
EP-0807665-B1 Flame retardant high temperature polyphthalamides having improved thermal stability BP AMOCO CORP (US) 2000-07-12 EP disclosed
US-5773500-A BROMINATED POLYSTYRENE WITH ANTIMONY COMPOUND AND MOLDING, CALCIUM OXIDE, MAGNESIUM OXIDE AND ZINC OXIDE AMOCO CORPORATION (US) 1998-06-30 US disclosed
EP-0812869-A2 Improved polyphthalamide composition AMOCO CORPORATION (US) 1997-12-17 EP disclosed
EP-0807665-A2 Flame retardant high temperature polyphthalamides having improved thermal stability AMOCO CORPORATION (US) 1997-11-19 EP disclosed
US-5665806-A MIXTURE WITH ALKALI METAL HALIDE, POTASSIUM IODIDE, AND COPPER IODIDE STABILIZER; HEAT RESISTANCE AMOCO CORPORATION (US) 1997-09-09 US disclosed
US-5585429-A CONTAINING LITHIUM HALIDE; REDUCED MELT VISCOSITY AMOCO CORPORATION (US) 1996-12-17 US disclosed
EP-0735082-A2 Polyphtalamide resin formulations AMOCO CORPORATION (US) 1996-10-02 EP disclosed
US-5436294-A Impact modifiers for improved ductility and rigidity AMOCO CORPORATION (US) 1995-07-25 US disclosed
US-5387645-A Synergistic blend of polyamide, functionalized polyolefin and functionalized styrene blocks and rubber blocks of ethylene, propylene, butylene and pentylene; maleic anhydride-modified AMOCO CORPORATION (US) 1995-02-07 US disclosed
EP-0477757-A2 Polyamide-Poly(aryl ether sulfone)blends AMOCO CORPORATION (US) 1992-04-01 EP disclosed
EP-0477027-A2 Improved polyphthalamide composition AMOCO CORPORATION (US) 1992-03-25 EP disclosed