Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27892613 | 1.00 | TAAR1 (0.43) | TAAR1SLC6A3DRD2SLC7A5HRH1 | |
| SCHEMBL2088592 | 0.93 | TAAR1 (0.46) | TAAR1SLC6A3DRD2SLC7A5HRH1 | |
| SCHEMBL1299443 | 0.86 | TAAR1 (0.58) | TAAR1SLC6A3DRD2HRH1GRIN2B | |
| SCHEMBL19274260 | 0.83 | THRA (0.51) | SLC6A3DRD2SLC6A2SLC6A4 | |
| SCHEMBL19506246 | 0.81 | THRA (0.49) | SLC6A3DRD2GRIN2BGRIN1SLC6A2 | |
| SCHEMBL17288587 | 0.79 | SLC6A3 (0.45) | SLC6A3DRD2GRIN2BGRIN1SLC6A2 | |
| SCHEMBL14378257 | 0.79 | SLC6A3 (0.49) | SLC6A3DRD2GRIN2BGRIN1SLC6A2 | |
| SCHEMBL2088590 | 0.79 | SLC6A3 (0.45) | SLC6A3DRD2GRIN2BGRIN1SLC6A2 | |
| SCHEMBL29412971 | 0.78 | GRIN2B (0.47) | TAAR1SLC6A3DRD2GRIN2BGRIN1 | |
| SCHEMBL40091 | 0.78 | GRIN2B (0.47) | TAAR1SLC6A3DRD2GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530562-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | Central Glass Company, Limited (JP) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004022521-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-18 | — | — | WO | disclosed |