SCHEMBL6232095

SCHEMBL6232095

CC(C)(C)c1c(F)ccc(OC(=O)O)c1O

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
MAPT P10636 2/20 0.31
POLB P06746 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
EPHX2 P34913 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
ALB P02768 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16239995 0.85 LMNA (0.34) LMNAMAPK1HTTRAB9ACYP4F2
SCHEMBL6233314 0.85 MAPT (0.41) LMNAMAPK1HTTRAB9AMAPT
SCHEMBL27199180 0.81 PTGDR2 (0.39) TDP1
SCHEMBL6234126 0.80 PTGDR2 (0.38) LMNAMAPTTDP1
SCHEMBL6230446 0.80 CYP2C19 (0.38) LMNAMAPK1RAB9AMAPTTDP1
SCHEMBL6233296 0.79 POLB (0.36) LMNAMAPTPOLBTDP1
SCHEMBL6232401 0.78 GLA (0.39) LMNAMAPK1RAB9AMAPTPOLB
SCHEMBL6232616 0.75 MAPT (0.38) LMNAMAPK1MAPT
SCHEMBL17030735 0.73 TYR (0.39) LMNAHTTPOLBTDP1ALB
SCHEMBL6233160 0.72 PTGDR2 (0.40) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed