Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096490 | 0.98 | ICMT (0.45) | ICMTNPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL6233653 | 0.89 | PIM1 (0.50) | ICMTNPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL7505384 | 0.84 | MTNR1B (0.59) | ICMTMTNR1AMTNR1BABL1EPHX2 | |
| SCHEMBL6232118 | 0.84 | HDAC3 (0.41) | NPC1RAB9AABL1 | |
| SCHEMBL5177248 | 0.84 | ICMT (0.46) | ICMTNPC1RAB9APIM1SLC22A12 | |
| SCHEMBL5604615 | 0.83 | MTNR1B (0.57) | ICMTMTNR1AMTNR1BABL1EPHX2 | |
| SCHEMBL11641239 | 0.83 | MTNR1B (0.57) | ICMTMTNR1AMTNR1BABL1EPHX2 | |
| Hydrochloric Acid SCHEMBL14744123 | 0.83 | ICMT (0.46) | ICMTNPC1RAB9APIM1SLC22A12 | |
| Hydrochloric Acid SCHEMBL7505379 | 0.83 | MTNR1B (0.57) | ICMTMTNR1AMTNR1BABL1EPHX2 | |
| SCHEMBL6230410 | 0.81 | POLB (0.54) | RAB9AABL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530562-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | Central Glass Company, Limited (JP) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004022521-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-18 | — | — | WO | disclosed |