Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232154 | 0.87 | CHRNA7 (0.42) | HDAC3HDAC1HDAC2POLBLMNA | |
| SCHEMBL6232362 | 0.84 | ICMT (0.46) | ABL1NPC1RAB9A | |
| SCHEMBL2096490 | 0.83 | ICMT (0.45) | ABL1NPC1RAB9A | |
| SCHEMBL6230410 | 0.83 | POLB (0.54) | HDAC3HDAC1HDAC2ABL1POLB | |
| SCHEMBL6231717 | 0.82 | LMNA (0.42) | POLBLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL12953554 | 0.78 | KIF11 (0.50) | HDAC3HDAC1HDAC2ABL1POLB | |
| SCHEMBL3400985 | 0.77 | ADRA2A (0.53) | ADRA2AABL1KCNH3GPR84 | |
| SCHEMBL28700733 | 0.75 | ABL1 (0.55) | ADRA2AABL1KCNH3GPR84 | |
| SCHEMBL10010025 | 0.74 | POLB (0.46) | HDAC3HDAC1HDAC2POLB | |
| SCHEMBL6231339 | 0.73 | TRPA1 (0.46) | ADRA2AABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530562-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | Central Glass Company, Limited (JP) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004022521-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-18 | — | — | WO | disclosed |