Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11660115 | 0.85 | TBXAS1 (0.50) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL6230409 | 0.81 | PRNP (0.49) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL6234251 | 0.80 | ALDH1A1 (0.47) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL6130779 | 0.78 | TBXAS1 (0.48) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL10550955 | 0.77 | HNF4A (0.50) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL6305533 | 0.77 | CLCN2 (0.43) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL6235442 | 0.76 | CDC25B (0.48) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL6234160 | 0.76 | POLB (0.43) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL6229996 | 0.76 | NR4A1 (0.41) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL31083578 | 0.74 | NR4A1 (0.54) | NR4A1NR4A2NR4A3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945450-B1 | FUSED HETEROCYCLIC BENZENECARBOXYLIC ACID AMIDE DERIVATIVES AND PGD2 ANTAGONISTS CONTAINING THE SAME | SHIONOGI & CO (JP) | 2005-05-11 | — | — | EP | disclosed |
| US-6069166-A | INHIBITORY ACTIVITY AGAINST INFILTRATION OF EOSIONOPHILS, AND ARE USEFUL AS DRUGS FOR TREATING NASAL BLOCKAGE | SHIONOGI & CO., LTD. (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0945450-A1 | FUSED HETEROCYCLIC BENZENECARBOXYLIC ACID AMIDE DERIVATIVES AND PGD2 ANTAGONISTS CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |