Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200400 | 0.97 | VCP (0.40) | VCPALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL28378850 | 0.94 | ALDH1A1 (0.38) | VCPALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL18274954 | 0.90 | VCP (0.40) | VCPALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL9641520 | 0.88 | VCP (0.39) | VCPALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL12972512 | 0.87 | GRIN2D (0.36) | VCPALDH1A1 | |
| SCHEMBL5859377 | 0.87 | ALDH1A1 (0.38) | VCPALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL27081188 | 0.86 | ALDH1A1 (0.36) | VCPALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL27081124 | 0.86 | ALDH1A1 (0.36) | VCPALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL25355025 | 0.82 | S100A4 (0.38) | VCPS100A4GPR35 | |
| SCHEMBL10976267 | 0.82 | TDP1 (0.38) | VCPALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028801-B1 | A METHOD OF PERFORMING A CHEMICAL REACTION | BRITISH NUCLEAR FUELS PLC (GB) | 2005-05-25 | — | — | EP | disclosed |
| US-6747178-B1 | Method of performing a chemical reaction | BRITISH NUCLEAR FUELS PLC (GB) | 2004-06-08 | — | — | US | disclosed |
| EP-1028801-A1 | A METHOD OF PERFORMING A CHEMICAL REACTION | British Nuclear Fuels PLC (GB) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999022857-A1 | A METHOD OF PERFORMING A CHEMICAL REACTION | BRITISH NUCLEAR FUELS PLC (GB) | 1999-05-14 | — | — | WO | disclosed |