Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 8/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232647 | 0.87 | PDCD1 (0.41) | PDCD1CD274KDM4EKMT2ALMNA | |
| SCHEMBL6233816 | 0.85 | SLC2A1 (0.51) | CD274SLC2A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL6271865 | 0.84 | SMN1; SMN2 (0.47) | PDCD1CD274SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL6233694 | 0.83 | SMN1; SMN2 (0.53) | CD274SLC2A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL6239778 | 0.83 | BCHE (0.65) | SLC2A1SMN1; SMN2KDM4EKMT2ABCHE | |
| SCHEMBL6230157 | 0.82 | KMT2A (0.58) | SLC2A1SMN1; SMN2KDM4EKMT2ABCHE | |
| SCHEMBL7840693 | 0.81 | KDM4E (0.57) | PDCD1CD274SLC2A1SMN1; SMN2KDM4E | |
| Bromide SCHEMBL11670771 | 0.81 | KDM4E (0.56) | PDCD1CD274SLC2A1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL11669913 | 0.81 | KDM4E (0.56) | PDCD1CD274SLC2A1SMN1; SMN2KDM4E | |
| SCHEMBL6235950 | 0.79 | PDCD1 (0.49) | PDCD1CD274KMT2AMEN1CTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |