Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611120 | 0.89 | TSHR (0.61) | KMT2ALTB4RLTB4R2MEN1SMN1; SMN2 | |
| SCHEMBL8827451 | 0.86 | KMT2A (0.54) | KMT2AALDH1A1GAAMEN1SMN1; SMN2 | |
| SCHEMBL7976117 | 0.86 | LTB4R (0.69) | KMT2ALTB4RLTB4R2MEN1SMN1; SMN2 | |
| SCHEMBL2088933 | 0.85 | KMT2A (0.53) | KMT2AALDH1A1GAAMEN1SMN1; SMN2 | |
| SCHEMBL7987092 | 0.85 | LTB4R (0.47) | KMT2ALTB4RLTB4R2ALDH1A1GAA | |
| SCHEMBL20463438 | 0.82 | MAOB (0.66) | KMT2AALDH1A1GAAMEN1SMN1; SMN2 | |
| SCHEMBL12493963 | 0.80 | ALDH1A1 (0.51) | KMT2AALDH1A1GAAMEN1SMN1; SMN2 | |
| SCHEMBL20463444 | 0.80 | ALDH1A1 (0.62) | KMT2AALDH1A1GAAMEN1SMN1; SMN2 | |
| SCHEMBL31025721 | 0.79 | NPC1 (0.75) | KMT2AMEN1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL340620 | 0.79 | NPC1 (0.75) | KMT2AMEN1SMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |