SCHEMBL6232819

SCHEMBL6232819

CCCC(Cc1ccccc1)OC(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 5/20 0.54
PRKCA P17252 2/20 0.52
PRKCD Q05655 2/20 0.52
LMNA P02545 1/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
TSHR P16473 2/20 0.46
TP53 P04637 1/20 0.46
CTSL P07711 2/20 0.45
CTSB P07858 2/20 0.45
MDM2 Q00987 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CYP2D6 P10635 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28714881 0.93 CTSK (0.51) CTSKPRKCAPRKCDLMNAKMT2A
SCHEMBL5726833 0.89 PRKCA (0.60) CTSKPRKCAPRKCDLMNAKMT2A
SCHEMBL15827354 0.89 PRKCA (0.60) CTSKPRKCAPRKCDLMNAKMT2A
SCHEMBL5725942 0.89 LMNA (0.55) PRKCAPRKCDLMNAKMT2AMEN1
SCHEMBL185257 0.88 CTSK (0.54) CTSKPRKCAPRKCDKMT2ATSHR
SCHEMBL4737298 0.87 PRKCA (0.53) CTSKPRKCAPRKCDLMNA
SCHEMBL10392447 0.87 TSHR (0.55) LMNAKMT2ATSHRTP53MDM2
SCHEMBL11794903 0.87 CTSK (0.44) CTSKPRKCAPRKCDLMNAKMT2A
SCHEMBL16673087 0.86 PRKCA (0.51) PRKCAPRKCDLMNAKMT2AMEN1
SCHEMBL8702956 0.86 TP53 (0.47) KMT2AMEN1TSHRTP53MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919397-B2 Two-component polysulphide adhesive/sealant HENKEL-TEROSON GMBH (HENKEL-TEROSON) (DE) 2005-07-19 US disclosed