Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.57 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723680 | 0.84 | FTO (0.58) | GSTP1FTOMEN1MAPTHTT | |
| SCHEMBL723679 | 0.84 | FTO (0.58) | GSTP1FTOMEN1MAPTHTT | |
| SCHEMBL329252 | 0.76 | FTO (0.67) | GSTP1FTOMEN1MAPTHTT | |
| SCHEMBL29355604 | 0.74 | GSTP1 (1.00) | GSTP1FTOMEN1MAPTHTT | |
| SCHEMBL329253 | 0.74 | GSTP1 (1.00) | GSTP1FTOMEN1MAPTHTT | |
| SCHEMBL726955 | 0.74 | FTO (0.57) | GSTP1FTOMEN1MAPTHTT | |
| SCHEMBL10682750 | 0.74 | FTO (0.65) | GSTP1FTOMEN1MAPTHTT | |
| Hydrochloric Acid SCHEMBL1244954 | 0.73 | FTO (0.56) | GSTP1FTOMEN1MAPTHTT | |
| SCHEMBL9223739 | 0.71 | FTO (0.60) | GSTP1FTOMEN1MAPTHTT | |
| SCHEMBL19350417 | 0.70 | FTO (0.65) | GSTP1FTOMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38723-E1 | Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells | MOLECULAR PROBES, INC. (US) | 2005-04-12 | — | — | US | disclosed |
| US-5576424-A | ANALYZING METABOLIC ACTIVITY OF ENZYMES | MOLECULAR PROBES, INC. (US) | 1996-11-19 | — | — | US | disclosed |
| US-5362628-A | Analyzing | MOLECULAR PROBES, INC. (US) | 1994-11-08 | — | — | US | disclosed |