2-Ethylhexanoic Acid

2-Ethylhexanoic Acid

SCHEMBL6233165

CCCCC(CC)C(=O)[O-].COc1ccc(C[N+](C)(C)CC(C)O)cc1OC

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.42
LDHA P00338 1/20 0.40
LTA4H P09960 2/20 0.39
EPHX2 P34913 1/20 0.39
TSHR P16473 1/20 0.38
STAT3 P40763 1/20 0.37
CYP3A4 P08684 1/20 0.35
SMPD1 P17405 1/20 0.35
PTGES O14684 1/20 0.35
ALOX5 P09917 1/20 0.35
PPARG P37231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Ethylhexanoic Acid SCHEMBL6233179 0.93 CA2 (0.43) CA2LDHALTA4HEPHX2STAT3
2-Ethylhexanoic Acid SCHEMBL6231597 0.92 CA2 (0.42) CA2LDHALTA4HEPHX2TSHR
2-Ethylhexanoic Acid SCHEMBL6235255 0.85 CTSK (0.42) CA2EPHX2PTGESALOX5PPARG
2-Ethylhexanoic Acid SCHEMBL23069473 0.82 CA2 (0.49) CA2PTGESALOX5PPARG
2-Ethylhexanoic Acid SCHEMBL6765272 0.80 CA2 (0.47) CA2LDHATSHRALOX5
Hexanoate SCHEMBL6235236 0.79 EPHX2 (0.47) LDHALTA4HEPHX2CYP3A4
Formic Acid SCHEMBL6770000 0.79 LDHA (0.47) CA2LDHASTAT3PPARG
Formic Acid SCHEMBL6770002 0.78 LDHA (0.48) CA2LDHASTAT3PPARG
2-Ethylhexanoic Acid SCHEMBL6237964 0.77 CTSK (0.42) CA2EPHX2PTGESALOX5PPARG
2-Ethylhexanoic Acid SCHEMBL5676956 0.76 CA2 (0.50) CA2LDHATSHRALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6730628-B2 TRIMERIZING AT LEAST ONE DIISOCYANATE IN THE PRESENCE OF 0.04-2% BY WEIGHT OF A TRIMERIZATION CATALYST CONTAINING A QUATERNARY OR AMINE SALT HAVING HYDROXY GROUPS DEGUSSA AG (DE) 2004-05-04 US claimed
US-20030158368-A1 Catalyst and process for preparing color-reduced polyisocyanates containing isocyanurate groups DEGUSA AG (DE) 2003-08-21 US claimed
US-20030153714-A1 Catalyst and process for preparing color-reduced polyisocyanates containing isocyanurate groups DEGUSA AG (DE) 2003-08-14 US claimed
US-6552154-B1 Trimerizing at least one diisocyanate in presence of such as N-(2-hydroxypropyl)-N,N-dimethyl-N-(3-methoxybenzyl)ammonium 2-ethylhexanoate DEGUSSA AG (DE) 2003-04-22 US claimed
EP-1085030-B1 Catalyst and process for preparing polyisocyanates having isocyanurate groups and low colouring DEGUSSA (DE) 2005-05-18 EP disclosed
US-6800714-B2 TRIMERIZING A DIISOCYANATE IN THE PRESENCE OF QUATERNARY AMMONIUM HYDROXIDES OR ESTERS DEGUSSA AG (DE) 2004-10-05 US disclosed
US-6730628-B2 TRIMERIZING AT LEAST ONE DIISOCYANATE IN THE PRESENCE OF 0.04-2% BY WEIGHT OF A TRIMERIZATION CATALYST CONTAINING A QUATERNARY OR AMINE SALT HAVING HYDROXY GROUPS DEGUSSA AG (DE) 2004-05-04 US disclosed
US-20030158368-A1 Catalyst and process for preparing color-reduced polyisocyanates containing isocyanurate groups DEGUSA AG (DE) 2003-08-21 US disclosed
US-20030153714-A1 Catalyst and process for preparing color-reduced polyisocyanates containing isocyanurate groups DEGUSA AG (DE) 2003-08-14 US disclosed
US-6552154-B1 Trimerizing at least one diisocyanate in presence of such as N-(2-hydroxypropyl)-N,N-dimethyl-N-(3-methoxybenzyl)ammonium 2-ethylhexanoate DEGUSSA AG (DE) 2003-04-22 US disclosed
EP-1085030-A2 Catalyst and process for preparing polyisocyanates having isocyanurate groups and low colouring Degussa-Hüls Aktiengesellschaft (DE) 2001-03-21 EP disclosed