Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182376 | 1.00 | ACE (0.38) | ACEL3MBTL1POLBHDAC1HDAC8 | |
| SCHEMBL3182383 | 1.00 | ACE (0.38) | ACEL3MBTL1POLBHDAC1HDAC8 | |
| SCHEMBL23346234 | 0.82 | ACE (0.34) | ACEL3MBTL1POLBHDAC1HDAC8 | |
| SCHEMBL26663809 | 0.82 | ACE (0.41) | ACEPOLBPTGER3PTGER2ITGB1 | |
| SCHEMBL26663803 | 0.82 | ACE (0.41) | ACEPOLBPTGER3PTGER2ITGB1 | |
| SCHEMBL7561265 | 0.79 | ITGB1 (0.41) | L3MBTL1POLBITGB1ITGA4 | |
| SCHEMBL28898088 | 0.78 | ACE (0.38) | ACEPOLBPTGER3PTGER2ITGB1 | |
| SCHEMBL9154699 | 0.76 | TPSAB1 (0.48) | POLBITGB1ITGA4 | |
| SCHEMBL22462730 | 0.75 | ABCB1 (0.41) | L3MBTL1ITGB1 | |
| SCHEMBL13482907 | 0.74 | NR1H2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |