Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153055 | 0.77 | L3MBTL1 (0.42) | TPSAB1TPSD1TPSG1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11499414 | 0.76 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1GAAKDM4ETSHR | |
| SCHEMBL6233244 | 0.76 | ACE (0.38) | ITGB1ITGA4POLB | |
| SCHEMBL3182376 | 0.76 | ACE (0.38) | ITGB1ITGA4POLB | |
| SCHEMBL3182383 | 0.76 | ACE (0.38) | ITGB1ITGA4POLB | |
| SCHEMBL21427791 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KMT2ANPC1PKMCYP2C9 | |
| SCHEMBL21408809 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KMT2ANPC1PKMCYP2C9 | |
| SCHEMBL18447374 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1GAAKDM4ETSHR | |
| SCHEMBL11719448 | 0.73 | KMT2A (0.70) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14879565 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447944-A | Activating cerebral metabolism and protection against anoxic brain damage | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-09-05 | — | — | US | disclosed |
| EP-0373226-B1 | Carbamoyl-2-pyrrolidinone compounds | TAIHO PHARMACEUTICAL CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5229402-A | Improving cerebral function | TAIHO PHARMACEUTICAL COMPANY, LTD. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0373226-A1 | Carbamoyl-2-pyrrolidinone compounds | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1990-06-20 | — | — | EP | disclosed |