Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233482 | 0.87 | GAA (1.00) | ALDH1A1GAAHPGDMAPTPOLB | |
| SCHEMBL6231464 | 0.87 | ALDH1A1 (0.77) | ALDH1A1GAAHPGDMAPTPOLB | |
| SCHEMBL6754962 | 0.84 | ALDH1A1 (0.72) | ALDH1A1GAAHPGDPOLBLMNA | |
| SCHEMBL6232212 | 0.83 | GAA (0.71) | ALDH1A1GAAHPGDMAPTPOLB | |
| SCHEMBL6254088 | 0.82 | ALDH1A1 (0.69) | ALDH1A1GAAHPGDMAPTPOLB | |
| SCHEMBL6254084 | 0.82 | ALDH1A1 (0.69) | ALDH1A1GAAHPGDMAPTPOLB | |
| SCHEMBL6252866 | 0.81 | ALDH1A1 (0.68) | ALDH1A1GAAHPGDMAPTPOLB | |
| SCHEMBL6232921 | 0.80 | ALDH1A1 (0.66) | ALDH1A1GAAHPGDPOLBHRH4 | |
| SCHEMBL24416092 | 0.77 | HRH4 (0.74) | ALDH1A1MAPTPOLBRXFP1HRH4 | |
| SCHEMBL1491507 | 0.77 | POLB (0.63) | ALDH1A1GAAHPGDMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |