Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | IDE | P14735 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233282 | 0.87 | ALDH1A1 (1.00) | GAAALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL6231464 | 0.85 | ALDH1A1 (0.77) | GAAALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL6232212 | 0.83 | GAA (0.71) | GAAALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL6754962 | 0.82 | ALDH1A1 (0.72) | GAAALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL18889270 | 0.81 | L3MBTL1 (0.69) | GAAALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL6231088 | 0.81 | L3MBTL1 (0.69) | GAAALDH1A1L3MBTL1HPGDMAPT | |
| SCHEMBL6254084 | 0.80 | ALDH1A1 (0.69) | GAAALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL6254088 | 0.80 | ALDH1A1 (0.69) | GAAALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL6252866 | 0.79 | ALDH1A1 (0.68) | GAAALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL6606228 | 0.78 | LMNA (1.00) | GAAALDH1A1L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |