Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.47 |
| ▸ | TYR | P14679 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231388 | 0.88 | PGAM1 (0.40) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL3899964 | 0.81 | ALOX5 (0.49) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL19228627 | 0.81 | HTT (0.43) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL5592696 | 0.79 | HPGD (0.45) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL5587469 | 0.78 | TYR (0.49) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL24452313 | 0.77 | HPGD (0.41) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL6232748 | 0.77 | HPGD (0.46) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL6233333 | 0.76 | ALOX5 (0.41) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL5677836 | 0.76 | HPGD (0.53) | HTTNPC1HPGDMAPK1RAB9A | |
| Acetic Acid SCHEMBL27851326 | 0.76 | HCAR2 (0.40) | HTTNPC1HPGDMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |