Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.39 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.39 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.39 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 4/20 | 0.38 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254681 | 0.88 | PDCD1 (0.41) | SMN1; SMN2KMT2AMEN1GAACD274 | |
| SCHEMBL6254676 | 0.88 | PDCD1 (0.41) | SMN1; SMN2KMT2AMEN1GAACD274 | |
| SCHEMBL6236884 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMEN1GAAGUCY1B2 | |
| SCHEMBL6233689 | 0.84 | CD274 (0.45) | SMN1; SMN2KMT2AMEN1CD274CTSA | |
| SCHEMBL6236773 | 0.83 | CTSA (0.41) | SMN1; SMN2KMT2ACD274CTSA | |
| SCHEMBL6231782 | 0.81 | MAOB (0.43) | SMN1; SMN2KMT2AMEN1GUCY1B2GUCY1A2 | |
| SCHEMBL6235441 | 0.80 | GPBAR1 (0.40) | SMN1; SMN2KMT2AMEN1GAACD274 | |
| SCHEMBL6252802 | 0.80 | GPBAR1 (0.40) | SMN1; SMN2KMT2AMEN1GAACD274 | |
| SCHEMBL6233374 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1GAACD274 | |
| SCHEMBL6235284 | 0.79 | PTPRZ1 (0.37) | CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |