Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CTSA | P10619 | 7/20 | 0.41 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.41 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.41 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.41 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231703 | 0.86 | LMNA (0.53) | SMN1; SMN2KMT2AMEN1GAARAB9A | |
| SCHEMBL6231706 | 0.86 | LMNA (0.53) | SMN1; SMN2KMT2AMEN1GAARAB9A | |
| SCHEMBL6233372 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1GAAHTT | |
| SCHEMBL6235475 | 0.85 | MTNR1A (0.46) | SMN1; SMN2HTTRAB9ACTSANPC1 | |
| SCHEMBL6276107 | 0.85 | MTNR1A (0.46) | SMN1; SMN2HTTRAB9ACTSANPC1 | |
| SCHEMBL6233373 | 0.84 | CD274 (0.42) | CTSAGUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL6236909 | 0.80 | NTRK1 (0.41) | SMN1; SMN2KMT2AMEN1GAARAB9A | |
| SCHEMBL6254676 | 0.79 | PDCD1 (0.41) | SMN1; SMN2KMT2AMEN1GAAHTT | |
| SCHEMBL6254681 | 0.79 | PDCD1 (0.41) | SMN1; SMN2KMT2AMEN1GAAHTT | |
| SCHEMBL6236888 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2KMT2AMEN1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |