Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 11/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252802 | 1.00 | GPBAR1 (0.40) | GPBAR1CTSACD274SMN1; SMN2LMNA | |
| SCHEMBL6231782 | 0.91 | MAOB (0.43) | SMN1; SMN2LMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL6236773 | 0.90 | CTSA (0.41) | GPBAR1CTSACD274SMN1; SMN2KMT2A | |
| SCHEMBL6233373 | 0.84 | CD274 (0.42) | CTSACD274 | |
| SCHEMBL6230535 | 0.82 | CD274 (0.46) | CTSACD274KMT2ATDP1MEN1 | |
| SCHEMBL6235445 | 0.81 | SMN1; SMN2 (0.44) | GPBAR1CD274SMN1; SMN2LMNAKMT2A | |
| SCHEMBL6233372 | 0.80 | SMN1; SMN2 (0.44) | CTSACD274SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6235514 | 0.80 | CD274 (0.40) | CTSACD274SMN1; SMN2KMT2A | |
| SCHEMBL6687667 | 0.78 | MAOB (0.59) | CD274LMNA | |
| SCHEMBL6687664 | 0.78 | MAOB (0.59) | CD274LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |