Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252802 | 0.91 | GPBAR1 (0.40) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6235441 | 0.91 | GPBAR1 (0.40) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6236773 | 0.84 | CTSA (0.41) | KMT2ASMN1; SMN2 | |
| SCHEMBL6236427 | 0.84 | MAOB (0.46) | MAOBMAOAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6233372 | 0.81 | SMN1; SMN2 (0.44) | KMT2AMEN1SMN1; SMN2GUCY1B2GUCY1A2 | |
| SCHEMBL6231785 | 0.80 | SMN1; SMN2 (0.39) | MAOBMAOAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6261792 | 0.78 | PTPRZ1 (0.43) | MAOBMAOAPPARDNR1H4LMNA | |
| SCHEMBL6232917 | 0.78 | PTPRZ1 (0.43) | MAOBMAOAPPARDNR1H4LMNA | |
| SCHEMBL6233373 | 0.77 | CD274 (0.42) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL6254676 | 0.76 | PDCD1 (0.41) | KMT2AMEN1SMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |