Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233136 | 0.94 | ALOX5 (0.57) | ALOX5ESR1LMNAMAPT | |
| SCHEMBL6232977 | 0.92 | ALOX5 (0.48) | ALOX5LTB4RCYSLTR2CYSLTR1HMGCR | |
| SCHEMBL6233674 | 0.89 | ALOX5 (0.56) | ALOX5ESR1LTB4R | |
| SCHEMBL6234043 | 0.83 | ALOX5 (0.49) | ALOX5ESR1HMGCRLMNA | |
| SCHEMBL6231507 | 0.81 | ALOX5 (0.57) | ALOX5ESR1LMNA | |
| SCHEMBL6233436 | 0.80 | CYSLTR2 (0.42) | ALOX5CYSLTR2CYSLTR1LMNACYP1A2 | |
| SCHEMBL5586919 | 0.77 | ESR1 (0.41) | ALOX5ESR1LTB4RHMGCR | |
| SCHEMBL6229050 | 0.77 | PPARG (0.50) | ESR1CYSLTR2CYSLTR1LMNACYP1A2 | |
| SCHEMBL6259480 | 0.76 | ESR1 (0.40) | ALOX5ESR1 | |
| SCHEMBL6235771 | 0.76 | ESR1 (0.40) | ALOX5ESR1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |