Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.47 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685478 | 0.81 | ALDH1A1 (0.51) | MAOBMAOARAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL6436010 | 0.78 | MAOB (0.69) | MAOBMAOASCN9A | |
| SCHEMBL6245446 | 0.78 | NR1H4 (0.47) | MAOBALKBH1 | |
| SCHEMBL7031067 | 0.77 | LMNA (0.52) | MAOBALKBH1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL27594865 | 0.77 | MAOB (0.51) | MAOB | |
| SCHEMBL2088391 | 0.76 | MAOB (0.44) | MAOBALKBH1SCN3ARAB9ASMN1; SMN2 | |
| SCHEMBL12934278 | 0.76 | KCNH2 (0.50) | MAOBALKBH1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1233634 | 0.75 | MAOB (0.46) | MAOBRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL42303 | 0.75 | BCHE (0.65) | MAOBMAOARAB9ASMN1; SMN2 | |
| SCHEMBL6321694 | 0.75 | MAOB (0.37) | MAOBALKBH1RAB9ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102151262-A | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP | 2011-08-17 | — | — | CN | disclosed |
| CN-102140064-A | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP | 2011-08-03 | — | — | CN | disclosed |
| CN-101444496-B | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP | 2011-04-13 | — | — | CN | disclosed |
| CN-101444496-A | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP (US) | 2009-06-03 | — | — | CN | disclosed |
| CN-100344616-C | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP (US) | 2007-10-24 | — | — | CN | disclosed |
| CN-1608055-A | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP (US) | 2005-04-20 | — | — | CN | disclosed |
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |