Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 3/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239029 | 0.82 | BAZ2B (0.64) | ALDH1A1POLBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL6234378 | 0.80 | HPGDS (0.68) | ALDH1A1PIK3CDPIK3CAPIK3CGHPGDS | |
| SCHEMBL27702482 | 0.80 | KMO (0.53) | ALDH1A1PIK3CDPIK3CAPIK3CGHPGDS | |
| SCHEMBL27970190 | 0.79 | POLB (0.74) | ALDH1A1POLBMRGPRX4HDAC1 | |
| SCHEMBL6236761 | 0.78 | DHODH (0.52) | ALDH1A1PIK3CDPIK3CAPIK3CGHPGDS | |
| SCHEMBL22050491 | 0.77 | PTPN1 (0.50) | ALDH1A1PIK3CDPIK3CAPIK3CGHPGDS | |
| SCHEMBL6237221 | 0.77 | DHODH (0.52) | ALDH1A1PIK3CDPIK3CAPIK3CGHPGDS | |
| SCHEMBL5934471 | 0.76 | MEN1 (0.57) | POLBHDAC6 | |
| SCHEMBL5934763 | 0.75 | TRPV1 (0.54) | DHODH | |
| SCHEMBL6235127 | 0.75 | BACE1 (0.57) | ALDH1A1PIK3CDPIK3CAPIK3CGKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |