SCHEMBL6233534

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16852620	0.98	CYP3A4 (0.53)	CYP3A4CYP2C19HIF1ACYP2D6HSD11B1
	SCHEMBL12335229	0.92	GRM5 (0.58)	CYP3A4CYP2C19HIF1ACYP2D6HSD17B10
	SCHEMBL5986519	0.89	OPRM1 (0.54)	CYP3A4CYP2C19HIF1ACYP2D6HSD17B10
	SCHEMBL10466780	0.87	USP2 (0.53)	CYP3A4CYP2C19HIF1ACYP2D6HSD17B10
	SCHEMBL18711489	0.85	CYP3A4 (0.55)	CYP3A4CYP2C19HIF1ACYP2D6HSD17B10
	SCHEMBL18711490	0.85	USP2 (0.55)	CYP3A4CYP2C19HIF1ACYP2D6HSD17B10
	SCHEMBL24279550	0.85	CYP3A4 (0.46)	CYP3A4CYP2C19HIF1ACYP2D6HSD11B1
	SCHEMBL23763347	0.83	CYP1A2 (0.52)	CYP3A4CYP2C19HIF1ACYP2D6HSD17B10
	SCHEMBL21078057	0.82	CYP3A4 (0.47)	CYP3A4CYP2C19HIF1ACYP2D6HSD17B10
	SCHEMBL4066199	0.81	HSD11B1 (0.54)	CYP3A4CYP2C19HIF1AHSD11B1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.