Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118823 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL8407230 | 0.78 | ALDH1A1 (0.50) | KCNJ1KCNH2ALDH1A1MAPTCYP1A2 | |
| SCHEMBL1966503 | 0.77 | KCNJ1 (0.44) | KCNJ1KCNH2ALDH1A1MAPTCYP1A2 | |
| SCHEMBL28051268 | 0.76 | MAPT (0.50) | KCNJ1KCNH2ALDH1A1MAPTCYP1A2 | |
| SCHEMBL424239 | 0.75 | TAAR1 (0.47) | ALDH1A1 | |
| SCHEMBL173199 | 0.75 | ALDH1A1 (0.50) | KCNJ1KCNH2ALDH1A1MAPTCYP1A2 | |
| SCHEMBL16806060 | 0.75 | ALDH1A1 (0.50) | KCNJ1KCNH2ALDH1A1MAPTCYP1A2 | |
| SCHEMBL16806066 | 0.75 | ALDH1A1 (0.50) | KCNJ1KCNH2ALDH1A1MAPTCYP1A2 | |
| SCHEMBL1964763 | 0.75 | ALDH1A1 (0.45) | KCNJ1KCNH2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2027813 | 0.75 | MAPT (0.45) | ALDH1A1MAPTCYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050170281-A1 | Method of cleaving labile functional groups from chemical compounds | NIMBLEGEN SYSTEMS, INC. | 2005-08-04 | — | — | US | disclosed |
| EP-1519941-A2 | A METHOD OF CLEAVING LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | Chemogenix GmbH (DE) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004001033-A2 | A METHOD OF CLEAVING LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | CHEMOGENIX GMBH (DE) | 2003-12-31 | — | — | WO | disclosed |