Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470432 | 0.89 | GRIA4 (0.46) | FFAR1 | |
| SCHEMBL1683176 | 0.81 | CA12 (0.42) | TAAR1 | |
| SCHEMBL9572884 | 0.81 | RIPK1 (0.47) | TAAR1AOC3TRPA1RIPK1ALDH1A1 | |
| SCHEMBL585216 | 0.81 | TAAR1 (0.56) | TAAR1AOC3TRPA1RIPK1ALDH1A1 | |
| SCHEMBL2092257 | 0.78 | RIPK1 (0.44) | TAAR1AOC3TRPA1RIPK1ALDH1A1 | |
| SCHEMBL11124275 | 0.77 | TSHR (0.38) | AOC3 | |
| SCHEMBL8489804 | 0.77 | CCR5 (0.41) | TAAR1FFAR1 | |
| SCHEMBL11124263 | 0.77 | TSHR (0.38) | AOC3 | |
| SCHEMBL9572677 | 0.77 | RIPK1 (0.43) | TAAR1AOC3TRPA1RIPK1ALDH1A1 | |
| SCHEMBL3632312 | 0.76 | TAAR1 (0.56) | TAAR1AOC3TRPA1RIPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4201707-A | Methine dyestuffs containing a phenyl azo group | BAYER AKTIENGESELLSCHAFT (DE) | 1980-05-06 | — | — | US | claimed |
| US-4138570-A | METHINE DYE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-06 | — | — | US | claimed |
| WO-2024075815-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | 国立大学法人大阪大学 | 2024-04-11 | — | — | WO | disclosed |
| US-20210309619-A1 | ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-10-07 | — | — | US | disclosed |
| US-11109593-B2 | Isoxazolin-5-one derivative and herbicide containing same as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-09-07 | — | — | US | disclosed |
| EP-3828176-A1 | ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | Hokko Chemical Industry Co., Ltd. (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-20200267985-A1 | ISOXAZOLIN-5-ONE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-08-27 | — | — | US | disclosed |
| WO-2020022350-A1 | ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | 北興化学工業株式会社 | 2020-01-30 | — | — | WO | disclosed |
| CN-110191880-A | Isoxazolidin-5-one derivative and herbicide containing the same as active ingredient | 北兴化学工业株式会社 | 2019-08-30 | — | — | CN | disclosed |
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| US-8603975-B2 | Cyclic peptide compounds | ASTELLAS PHARMA INC. (JP) | 2013-12-10 | — | — | US | disclosed |
| US-4933355-A | ALDOSE REDUCTASE INHIBITORS | SANKYO COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0337819-A1 | Thiazole derivatives, their preparation and their use in the treatment of diabetes complications | Sankyo Company Limited (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-4859759-A | Siloxane containing benzotriazolyl/tetraalkylpiperidyl substituent | KIMBERLY-CLARK CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0135349-B1 | CONDENSED SEVEN-MEMBERED RING COMPOUNDS AND THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1988-11-02 | — | — | EP | disclosed |
| US-4591458-A | ENZYME INHIBITORS; HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-05-27 | — | — | US | disclosed |
| US-4584303-A | ANALGESICS | THE BOC GROUP, INC. (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0160422-A1 | N-Aryl-N-(4-Piperidinyl)amides and pharmaceutical compositions and methods employing such compounds | Anaquest, Inc. (US) | 1985-11-06 | — | — | EP | disclosed |
| US-4548932-A | ANGIOTENSIN INHIBITOR, HYPOTENSIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0135349-A1 | Condensed seven-membered ring compounds and their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200267985-A1 | ISOXAZOLIN-5-ONE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | HAX1, CYP4X1, CANX | TAAR1 2133/4885AOC3 1126/4885TRPA1 727/4885 |
| US-11109593-B2 | Isoxazolin-5-one derivative and herbicide containing same as active ingredient | HAX1, CYP4X1, CANX | TAAR1 2133/4885AOC3 1126/4885TRPA1 727/4885 |
| US-20210309619-A1 | ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | HAX1, CYP4X1, CNPY2 | TAAR1 2015/4885AOC3 437/4885TRPA1 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.