Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | LPO | P22079 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2088662 | 0.81 | ALDH1A1 (0.50) | IDO1AGXTLTA4H | |
| SCHEMBL2094203 | 0.81 | MAOB (0.51) | IDO1AGXTMAOB | |
| SCHEMBL6232418 | 0.80 | LTA4H (0.43) | IDO1LTA4HTAAR1MAOB | |
| SCHEMBL6235370 | 0.77 | IDO1 (0.42) | IDO1AGXTTAAR1MAOBIDH1 | |
| SCHEMBL2099512 | 0.75 | CHRM2 (0.66) | IDO1AGXTLTA4HCHRM2CHRM1 | |
| Ammonia Solution, Strong SCHEMBL25291856 | 0.72 | LTA4H (0.51) | IDO1AGXTLTA4HDHFRCHRM2 | |
| SCHEMBL29194587 | 0.71 | ALDH1A1 (0.68) | IDO1AGXTLTA4HDHFRTAAR1 | |
| SCHEMBL27318933 | 0.71 | TAAR1 (0.46) | IDO1AGXTLTA4HDHFRCHRM2 | |
| SCHEMBL2092574 | 0.70 | LTA4H (0.67) | IDO1AGXTLTA4HCHRM2CHRM1 | |
| SCHEMBL31739258 | 0.70 | LTA4H (0.67) | IDO1AGXTLTA4HCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | claimed |
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |