Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232418 | 0.81 | LTA4H (0.43) | IDO1TAAR1MAPTMEN1KMT2A | |
| SCHEMBL2093905 | 0.80 | RAB9A (0.38) | IDO1AGXTTAAR1MAPTALDH1A1 | |
| SCHEMBL6233676 | 0.77 | IDO1 (0.47) | IDO1AGXTTAAR1IDH1GPR52 | |
| SCHEMBL3300303 | 0.72 | TAAR1 (0.60) | IDO1AGXTTAAR1ALDH1A1DAO | |
| SCHEMBL6238401 | 0.70 | IDO1 (0.39) | IDO1TAAR1MEN1KMT2AKDM4E | |
| SCHEMBL2091553 | 0.69 | ALDH1A1 (0.46) | IDO1AGXTMAPTKMT2AKDM4E | |
| SCHEMBL2095762 | 0.69 | LTA4H (0.39) | IDO1AGXTTAAR1MAPTMEN1 | |
| SCHEMBL2095241 | 0.69 | LTA4H (0.43) | IDO1TAAR1KDM4EALDH1A1IDH1 | |
| SCHEMBL694798 | 0.68 | KDM4E (0.47) | IDO1TAAR1MAPTMEN1KMT2A | |
| SCHEMBL205608 | 0.68 | TAAR1 (0.40) | IDO1AGXTTAAR1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | claimed |
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |