Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236466 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAKMT2AMEN1GAA | |
| SCHEMBL12642510 | 0.85 | KMT2A (0.48) | SMN1; SMN2LMNAKMT2AMEN1GAA | |
| SCHEMBL6232179 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2APLNRLMNAKMT2AMEN1 | |
| SCHEMBL6230449 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2APLNRLMNAKMT2AMEN1 | |
| SCHEMBL6252823 | 0.79 | KMT2A (0.47) | SMN1; SMN2APLNRLMNAKMT2AMEN1 | |
| SCHEMBL6235445 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2APLNRLMNAKMT2AMEN1 | |
| SCHEMBL6236017 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAKMT2AMEN1GAA | |
| SCHEMBL6252802 | 0.73 | GPBAR1 (0.40) | SMN1; SMN2LMNAKMT2AMEN1GAA | |
| SCHEMBL6235441 | 0.73 | GPBAR1 (0.40) | SMN1; SMN2LMNAKMT2AMEN1GAA | |
| SCHEMBL6687664 | 0.73 | MAOB (0.59) | LMNACD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |