Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231785 | 0.92 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL6236777 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2GPBAR1KMT2AMEN1TAAR1 | |
| SCHEMBL6233378 | 0.84 | CD274 (0.43) | KMT2AMEN1CD274PDCD1ALDH1A1 | |
| SCHEMBL6230537 | 0.82 | BCHE (0.52) | SMN1; SMN2KMT2AMEN1CD274PDCD1 | |
| SCHEMBL6252802 | 0.81 | GPBAR1 (0.40) | SMN1; SMN2GPBAR1KMT2AMEN1CD274 | |
| SCHEMBL6235441 | 0.81 | GPBAR1 (0.40) | SMN1; SMN2GPBAR1KMT2AMEN1CD274 | |
| SCHEMBL6233374 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1TAAR1CD274 | |
| SCHEMBL6235523 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2GPBAR1KMT2AMEN1EGFR | |
| SCHEMBL6233698 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2GPBAR1KMT2AMEN1CD274 | |
| SCHEMBL6236888 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2KMT2AMEN1TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |