Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234217 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAKMT2AMEN1GAA | |
| SCHEMBL6233698 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2APLNRLMNAKMT2AMEN1 | |
| SCHEMBL6252823 | 0.79 | KMT2A (0.47) | SMN1; SMN2APLNRLMNAKMT2AMEN1 | |
| SCHEMBL6232175 | 0.79 | AR (0.38) | SMN1; SMN2LMNAKMT2AMEN1GAA | |
| SCHEMBL6230449 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2APLNRLMNAKMT2AMEN1 | |
| SCHEMBL6235445 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2APLNRLMNAKMT2AMEN1 | |
| SCHEMBL6687667 | 0.74 | MAOB (0.59) | LMNA | |
| SCHEMBL6687664 | 0.74 | MAOB (0.59) | LMNA | |
| SCHEMBL6236017 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAKMT2AMEN1GAA | |
| SCHEMBL6235441 | 0.72 | GPBAR1 (0.40) | SMN1; SMN2LMNAKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |