Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624711 | 0.75 | MEN1 (0.45) | KDM4EALDH1A1ALPLHPGDHSD17B10 | |
| SCHEMBL5210609 | 0.71 | SMN1; SMN2 (0.49) | KDM4EALDH1A1ALPLHPGDHSD17B10 | |
| SCHEMBL1701209 | 0.70 | HSP90AA1 (0.48) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL1701438 | 0.70 | HTR7 (0.41) | KDM4EHPGDMAPTAPOBEC3GTDP1 | |
| SCHEMBL28454459 | 0.68 | RPS6KB2 (0.50) | KDM4EALDH1A1HPGDHSD17B10RPS6KB2 | |
| SCHEMBL2591881 | 0.68 | MAPT (0.45) | KDM4EALDH1A1ALPLHPGDHSD17B10 | |
| SCHEMBL26672756 | 0.68 | GPR119 (0.59) | KDM4EALDH1A1ALPLHPGDHSD17B10 | |
| SCHEMBL2585043 | 0.67 | TTK (0.40) | KDM4EALDH1A1HPGDHSD17B10ADORA2A | |
| SCHEMBL11624487 | 0.66 | RPS6KB2 (0.44) | KDM4EALDH1A1ALPLHPGDHSD17B10 | |
| SCHEMBL1701865 | 0.65 | FYN (0.43) | KDM4EALDH1A1ALPLHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563776-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | Calcimedica, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011139489-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-11-10 | — | — | WO | disclosed |