Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560312 | 0.91 | PARP1 (0.38) | PARP1CDC7IKBKBCHUK | |
| SCHEMBL28590450 | 0.74 | MEN1 (0.42) | TLR8KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL17786111 | 0.73 | PARP1 (0.38) | PARP1CDC7TLR8IKBKBCHUK | |
| SCHEMBL7449857 | 0.72 | PARP1 (0.38) | PARP1TLR8CNR1 | |
| SCHEMBL27811001 | 0.72 | BID (0.40) | TLR8MEN1MAPTKMT2A | |
| SCHEMBL17786119 | 0.70 | IKBKB (0.47) | PARP1CDC7IKBKBCHUK | |
| SCHEMBL7158098 | 0.69 | BID (0.51) | TLR8KDM4EMEN1MAPTKMT2A | |
| SCHEMBL2470964 | 0.68 | CNR1 (0.39) | CNR2MEN1MAPTHTTKMT2A | |
| SCHEMBL29057838 | 0.68 | PARP1 (0.38) | PARP1MAPTHTT | |
| SCHEMBL5808501 | 0.67 | HTR2C (0.44) | PARP1CDC7TLR8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049676-B1 | 4- ARYL(PIPERIDIN-4-YL)] AMINOBENZAMIDES WHICH BIND TO THE DELTA-OPIOID RECEPTOR | ORTHO MCNEIL PHARM INC (US) | 2005-10-12 | — | — | EP | disclosed |
| EP-1049676-A1 | 4- ARYL(PIPERIDIN-4-YL)] AMINOBENZAMIDES WHICH BIND TO THE DELTA-OPIOID RECEPTOR | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999033806-A1 | 4-[ARYL(PIPERIDIN-4-YL)] AMINOBENZAMIDES WHICH BIND TO THE DELTA-OPIOID RECEPTOR | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 1999-07-08 | — | — | WO | disclosed |