Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 3/20 | 0.36 |
| ▸ | CHUK | O15111 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233771 | 0.91 | PARP1 (0.36) | PARP1CDC7IKBKBCHUK | |
| SCHEMBL17786111 | 0.75 | PARP1 (0.38) | PARP1CDC7IKBKBCHUKPARP2 | |
| SCHEMBL17786119 | 0.73 | IKBKB (0.47) | PARP1CDC7IKBKBCHUKPARP2 | |
| SCHEMBL7449857 | 0.70 | PARP1 (0.38) | PARP1 | |
| SCHEMBL5808501 | 0.70 | HTR2C (0.44) | PARP1CDC7IKBKBCHUKPARP2 | |
| SCHEMBL28325510 | 0.70 | PARP1 (0.57) | PARP1CDC7IKBKBCHUKPARP2 | |
| SCHEMBL20400462 | 0.68 | PARP1 (0.44) | PARP1IKBKBCHUKPARP2 | |
| SCHEMBL27602072 | 0.68 | PARP1 (0.44) | PARP1CDC7IKBKBCHUKPARP2 | |
| SCHEMBL28853765 | 0.68 | PARP1 (0.52) | PARP1CDC7IKBKBCHUKPARP2 | |
| SCHEMBL3809365 | 0.67 | PARP1 (0.51) | PARP1CDC7IKBKBCHUKPARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576105-B2 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | JANSSEN PHARMACEUTICA, NV (BE) | 2009-08-18 | — | — | US | disclosed |
| US-20060106066-A1 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | BAXTER ELLEN W | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106066-A1 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | OPRD1, OPRK1, OPRM1 | PARP1 2731/4885CDC7 4786/4885IKBKB 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.