Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646940 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTNPSR1HPGDPOLB | |
| SCHEMBL4314662 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTNPSR1POLBKDM4E | |
| SCHEMBL21519389 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTNPSR1HPGDPOLB | |
| SCHEMBL7784647 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTNPSR1HPGDPOLB | |
| SCHEMBL7644933 | 0.76 | GPR35 (0.43) | ALDH1A1MAPTNPSR1KDM4ELMNA | |
| SCHEMBL4309273 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPTNPSR1HPGDPOLB | |
| SCHEMBL17146210 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPTNPSR1HPGDPOLB | |
| SCHEMBL5739943 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MAPTNPSR1HPGDPOLB | |
| SCHEMBL27617317 | 0.74 | LMNA (0.41) | ALDH1A1MAPTNPSR1HPGDPOLB | |
| SCHEMBL18185034 | 0.74 | LMNA (0.48) | ALDH1A1MAPTNPSR1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20050170281-A1 | Method of cleaving labile functional groups from chemical compounds | NIMBLEGEN SYSTEMS, INC. | 2005-08-04 | — | — | US | disclosed |
| EP-1519941-A2 | A METHOD OF CLEAVING LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | Chemogenix GmbH (DE) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004001033-A2 | A METHOD OF CLEAVING LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | CHEMOGENIX GMBH (DE) | 2003-12-31 | — | — | WO | disclosed |