Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6194231 | 0.91 | TAAR1 (0.45) | HRH1MAOATAAR1IDO1MPO | |
| SCHEMBL15787560 | 0.84 | NOS3 (0.41) | HRH1MAOATAAR1MPO | |
| SCHEMBL12075878 | 0.84 | MAOA (0.41) | HRH1MAOATAAR1MPOHTR2A | |
| SCHEMBL20082375 | 0.84 | MAOA (0.41) | HRH1MAOATAAR1IDO1MPO | |
| SCHEMBL7069858 | 0.83 | MAOA (0.56) | HRH1MAOAHTR2A | |
| SCHEMBL1014548 | 0.80 | TAAR1 (0.60) | TAAR1IDO1HTR2A | |
| SCHEMBL7436821 | 0.80 | MAOA (0.59) | HRH1MAOA | |
| SCHEMBL29263635 | 0.79 | TAAR1 (0.71) | HRH1MAOATAAR1IDO1 | |
| SCHEMBL29263674 | 0.79 | TAAR1 (0.71) | HRH1MAOATAAR1IDO1 | |
| SCHEMBL6231349 | 0.79 | TAAR1 (0.71) | HRH1MAOATAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530562-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | Central Glass Company, Limited (JP) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004022521-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-18 | — | — | WO | disclosed |