Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 15/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029329 | 0.90 | GALR1 (0.42) | PIK3CADRD2VNN1PIK3R1KDM4E | |
| SCHEMBL4832454 | 0.89 | DRD2 (0.39) | DRD2VNN1KDM4EALDH1A1POLB | |
| SCHEMBL5551996 | 0.85 | GALR1 (0.47) | DRD2 | |
| SCHEMBL6239105 | 0.82 | HTT (0.44) | VNN1KDM4EALDH1A1POLBHPGD | |
| SCHEMBL6428940 | 0.81 | PIK3CA (0.38) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL4829744 | 0.80 | DRD2 (0.50) | DRD2 | |
| SCHEMBL4832495 | 0.80 | DRD2 (0.50) | DRD2 | |
| SCHEMBL6231894 | 0.80 | MAP3K8 (0.40) | DRD2VNN1KDM4EALDH1A1POLB | |
| SCHEMBL7190657 | 0.79 | MAP3K8 (0.39) | DRD2VNN1KDM4EALDH1A1POLB | |
| SCHEMBL5029035 | 0.78 | GALR1 (0.44) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |