Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405019 | 0.91 | GAA (0.64) | GAATDP1CTSKMAOAMAOB | |
| SCHEMBL15728746 | 0.91 | CTSK (0.50) | GAATDP1CTSKMAOAMAOB | |
| SCHEMBL8032622 | 0.88 | GAA (0.69) | GAATDP1CTSKMAOAMAOB | |
| SCHEMBL1784924 | 0.87 | CTSK (0.51) | GAATDP1CTSKMAOAMAOB | |
| SCHEMBL156233 | 0.86 | TDP1 (0.46) | GAATDP1CTSKMAOAMAOB | |
| SCHEMBL6355605 | 0.85 | GAA (0.54) | GAATDP1CTSKMAOAMAOB | |
| SCHEMBL1936376 | 0.85 | ALDH1A1 (0.52) | GAATDP1CTSKMAOAMAOB | |
| SCHEMBL4578241 | 0.83 | MEN1 (0.47) | GAATDP1CTSKMAOAMAOB | |
| SCHEMBL432412 | 0.83 | MAOA (0.51) | GAATDP1CTSKMAOAMAOB | |
| SCHEMBL9555151 | 0.82 | GAA (0.53) | GAATDP1CTSKMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |